DEPTOR and neoplasm: Still, in colon cancer, DEPTOR acts as a tumor promoter that is targeted by the Wnt/b‐Catenin/c‐Myc signaling pathway.[37] Similarly, in T‐cell leukemia, the NOTCH1 signal is abnormally activated, promoting cell survival and proliferation through DEPTOR.[38] Results of in vitro and in vivo experiments indicated that DEPTOR overexpression could promote proliferation, metastasis, and glycolysis of GC cells.