GPR183 and systemic lupus erythematosus: To explore how EBI2 was down‐regulated in monocytes/macrophages of SLE patients and mice, we first treated murine peritoneal exudate macrophages (PEMs) with 7α, 25‐OHC, which did not affect the mRNA and protein expression of EBI2 (Figure S2J,K, Supporting Information).