Hematoxylin and eosin (H&E) staining demonstrated worsened histologic damage in Ebi2‐cKO mice, as evidenced by enlarged glomerulus and pulmonary hemorrhage (Figure 8B,C), more diffused immune cells in the red pulp of spleen, and more severe vacuolization in spleen and liver (Figure 8D,E). Here, GPR183 is linked to Pulmonary hemorrhage.