TGFB3 and systemic lupus erythematosus: Intriguingly, serum concentrations of these up‐regulated genes in Ebi2‐cKO monocytes were previously reported to be increased in SLE patients,[30] and TGF‐β3 was reported to negatively regulate SLE.[31] Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis also revealed that cytokine and cytokine receptor interaction were the top two enriched signaling pathways (Figure 6B).