Prior to conducting the assay, we identified a subset panel of factors known to mediate the induction of apoptosis in tumor cells: IL-27 [41], IL-1b [42], IL-2 [43], CXCL10 [44], IL-12p70 [45], G-CSF [46], IFN-g [47], TNF-a [48], IFN-a [49], CCL2 [50], IL-9 [51], TNF-b [52], TRAIL [53], IL-18 [54], IL-21 [55], TSLP [56]. The gene discussed is IL21; the disease is neoplasm.