However, the M1 protein VGF was only nominally significant at classifying AD in Caucasian AUC = 0.6030 (p = 0.0406, CI = 0.4887–0.7173), yet highly significant in African Americans AUC = 0.7593 (p = 5.03e-06, CI = 0.6634–0.8552). The gene discussed is VGF; the disease is Alzheimer disease.