Consistent with the TMT-MS protein measurements, proteins measured by SRM within M7 (GAPDH and YWHAG) and M8 (YWAHB and PPIA) had strong elevations (p < 0.001) in abundance in AD in both races, whereas proteins in M12 (SMOC1, PARK7, and LDHB) had a greater magnitude of change in Caucasians than African Americans with AD (for a list of all M12 members, see Supplemental Table 6). Here, GAPDH is linked to Alzheimer disease.