However, whether lnc-LRRTM4 binds to LRRTM4 promoter directly to enhance the transcription or recruits transcription factor to the LRRTM4 promoter region to exert its transcription function remain unclear, and the way in which LRRTM4 participates in CRC progression still needs further study. This evidence concerns the gene LRRTM4 and colorectal carcinoma.