], the effects of the GLP-1 RA efpeglenatide on MACE, expanded MACE, renal composite outcome, MACE, or death outcome, and hospitalizations for heart failure (hHF), as well as adverse events, appeared to be independent of concurrent SGLT2i use, as judged by point estimates in patients receiving compared with those not receiving baseline SGLT2i and lack of any formal interactions. Here, GLP1R is linked to heart failure.