GCG and type 2 diabetes mellitus: In adults with T2D, eGFR ≥ 60 mL/min/1.73 m2 plus albuminuria (≥ 200 mg/g) or eGFR 30–59 mL/min/1.73 m2 independently of albuminuria and HbA1c above target despite triple therapy, quadruple therapy including metformin, SGLT2i, GLP-1 RA and a fourth AD or IBT MAY BE CONSIDERED to improve glycemic control.