ST6GALNAC5 and prostate adenocarcinoma: In TCGA-PRAD dataset, ST6GALNAC5 was the only gene consistently up-regulated in PCa samples with lymph node metastatic (N1, n = 80) compared with normal prostate glands (N, n = 52; p < 0.05) and PCa samples without lymph node metastasis (N0, n = 345; p < 0.01; Fig. 1A).