Since VX-11e (an ERK inhibitor), Entospletinib (a Syk inhibitor), and Trametinib (a MEK inhibitor) have been reported to inhibit the phosphorylation of ERK [30–33], phospho-ERK levels in PCa cells with different expression levels of ST6GALNAC5 were tested. The gene discussed is SYK; the disease is posterior cortical atrophy.