CDKN1A and myotonic dystrophy type 1: Moreover, supporting our results, RNAseq on muscle samples from DM1 patients and controls showed that genes related to SASP factors (e.g. CXCL14, CXCL16, and MMP2) or cell cycle inhibitors (e.g. CDKN1A, TP63)55, are negatively correlated with muscle strength in DM151.