For example, a breast cancer VLP vaccine that attaches HER2 antigenic epitopes to 30 nm icosahedral cowpea mosaic virus (CPMV) could effectively induce antigen-specific responses and tumor protection in a mouse model.292 In addition, the tumor-associated carbohydrate antigen MUC1 can be covalently linked to Qβ, a self-assembled icosahedral shell VLP with 25 nm. Here, ERBB2 is linked to neoplasm.