These included the histone acetyl transferases KAT6A (MOZ/MYST3) and CREBBP (CBP/KAT3A), as well as the kinase HIPK2. It is also noteworthy that we observed enrichment of several biological pathways related to cancer and diverse signaling pathways in our GSEA of the upregulated genes unique to 2KR-MYB (Fig. 2A). The gene discussed is CREBBP; the disease is cancer.