Moreover, individuals with loss-of-function mutations in MFSD2A (a.k.a Microcephaly 15 Autosomal Recessive) present with severe microcephaly and hypomyelination, indicating that LPC transport via Mfsd2a is essential for normal human brain development and myelination (22, 23, 24, 25). Here, MFSD2A is linked to microcephaly.