These analyses showed that the emotional subscale had moderate accuracy in discriminating between cases and non-cases of MDD (AUC range = 0.67–0.85), and high accuracy in discriminating cases of GAD (AUC range = 0.80–0.93) and any anxiety disorder (0.74–0.83) from non-cases (see Table 3). This evidence concerns the gene GAD1 and major depressive disorder.