IL6 and Insulin resistance: Increased TFA consumption may disrupt metabolic pathways and oocyte quality (Cekici and Akdevelioglu, 2019) through mechanisms including down regulation of peroxisome proliferator-activated receptor gamma (PPAR-γ) expression (Clark, 2002; Saravanan et al., 2005), increased inflammatory markers such as C-reactive protein, Interleukin-6, and E-selectin (Baer et al., 2004), as well as a reduction in insulin resistance (Lefevre et al., 2005).