Consistently, HALLMARK annotation for the m6A DEGs among clusters A and B, the Notch, Hedgehog, and Wnt beta catenin signaling pathway also ranked as the top and is shown in Fig. 5D. These function results showed that these ten hub regulatory factors might affect the survival and development of CSCs in HCC patients. This evidence concerns the gene CTNNB1 and hepatocellular carcinoma.