In order to confirm our speculation, we sorted out 3_Positive (CD24+EPCAM+CD133+) LCSCs and 3_Negative (CD24−EPCAM−CD133−) liver cancer cells by flow cytometry in both Hep3B and Huh7 cells (Figure S4D, S4F, S4G), then we discovered that the expression of these ten m6A regulatory factors were highly expressed in 3_Positive (CD24+EPCAM+CD133+) LCSCs from Hep3B and Huh7 cells by RT-qPCR (Fig. 3F–G). The gene discussed is EPCAM; the disease is liver cancer.