TARDBP and amyotrophic lateral sclerosis: A recently described phenotype governed by the mislocalization of TDP-43 in ALS-TDP and FTD-TDP is a failure of TDP-43 to repress the inclusion of cryptic exons (CEs) in several RNA transcript targets of TDP-43 [4, 23, 24, 29, 33, 39, 50].