As deeper sequencing increased the number of cells presumed to be affected by TDP-43 dysfunction due to the presence of STMN2 and/or KALRN CE junctions, we again performed differential gene expression analysis on the largest neuronal subgroup (L2–L3 intratelencephalic neurons) between nuclei containing a CE (either STMN2 and/or KALRN) and nuclei not containing a CE for the deeply sequenced subject; C9-FTD 4 (Supplementary Table 5, online resource). This evidence concerns the gene KALRN and frontotemporal dementia.