KALRN and amyotrophic lateral sclerosis: Using the bulk RNA sequencing dataset from Liu et al. (2019), which described the transcriptome of TDP-43 positive and negative nuclei from FTD-ALS postmortem brain with TDP-43 pathology [30], we confirmed the presence of a CE junction in the KALRN gene between exons 56 and 57, near the 3 ́ end of the gene (Supplementary Fig. 2b, online resource).