However, the SNV rs72821893 (KRT25) was recently associated with the individual’s response to asthma treatment.29 Leusink, et al.29 (2016), when studying a population of 110 children with asthma diagnosis that was not well controlled despite inhaled corticosteroid (ICS) treatment and the 17q12-21 locus – previously associated with childhood asthma – found that the rs72821893 in KRT25 gene was associated with the lung function and airway hyperresponsiveness (AHR) to methacholine, and additionally with ICS treatment response.29 This evidence concerns the gene KRT25 and asthma.