NFKBIA and infection: This lack of BoHV-1-induced NF-κB activation in MDBK cells is not due to cell type-specific peculiarities with regard to IκBα degradation and/or NF-κB activation, as we showed earlier (9) and confirmed here (Fig. 1B) that infection of MDBK cells with the porcine alphaherpesvirus PRV does result in degradation of the IκBα protein.