The qPCR results indicated that with the exception of ITGB2, all NRGs were significantly overexpressed in ANCA-GN patients compared to healthy controls, and the expression levels were found to be statistically significant (p<0.01) between the ANCA-GN group and the healthy group (Figures 10A-F). The gene discussed is ITGB2; the disease is ganglioneuroma.