By weighting the normalized expression level of HSP90AB1 and RSAD2 to the regression coefficients of the multivariate logistic regression analysis, we established an SLE risk score model (SLE risk score = normalized expression level of RSAD2 * 1.469 - normalized expression level of HSP90AB1 * 4.389) and VTE risk score model (VTE risk score = normalized expression level of RSAD2 * 0.413 - normalized expression level of HSP90AB1 * 5.184). This evidence concerns the gene HSP90AB1 and systemic lupus erythematosus.