Mice were challenged bilaterally with TRAMP-C2 cells and when they developed right flank tumors of approximately 50 mm3, they were treated intratumorally only in the right flank tumor with HBSS, cyto-IL-15, ADU-S100 or combination of cyto-IL-15 and ADU-S100 (as described in methods). This evidence concerns the gene IL15 and neoplasm.