The presence of normal PT, PTT, fibrin degradation product (FDP) may be used in some cases to distinguish TTP from DIC as coagulation is usually intact in TPP.13,14 Similar to DIC, HUS has several shared characteristics with TTP but typically presents in children whereas acquired TTP more often develops in adults.13 Further, HUS also commonly presents with mild to moderate thrombocytopenia and severe renal dysfunction, though there are exceptions to this as well.13 Additional laboratory tests measuring ADAMTS13 activity and anti-ADAMTS13 antibodies can be used to confirm TTP. This evidence concerns the gene ADAMTS13 and Abnormal renal physiology.