Among the 3 groups compared by GNRI classification, age, lymphocyte count, neutrophil count, serum creatinine, triglycerides, LDL cholesterol, C-reactive protein, diastolic blood pressure, gender, race, marital status, cardiovascular disease, diabetes mellitus, chronic kidney disease, smoking, and alcohol consumption were statistically different (P < 0.05). The gene discussed is CRP; the disease is chronic kidney disease.