SMOC2 and hydrops fetalis: Masson staining also showed that the blue-stained collagen fibers in HF + sh-SMOC2 + SRI-01138 group were significantly more than 1 HF + sh-SMOC2 group (P < 0.01, Figure 5c), confirming that SRI-011381 inhibited the effect of SMOC2 knockdown in HF rats.