RUNX2 and osteoporosis: Studies have revealed thatosteoporosis induced by glucocorticoid therapy leads todecreased acetylation of H3K9/K14 and H4K12 in theregulatory regions of the RUNX2 and OSX genes andincreases the hyperacetylation of H3K9/K14 and H4K12in the PPARγ2 regulatory region in bone marrow-derivedMSCs from osteoporosis.