In the course of EMT, cancer cells start to lose expression or function of epithelial markers, such as E-cadherin and gain mesenchymal markers, such as vimentin, mesenchymal neural cadherin (N-cadherin), integrins (α2β1, α5β1), collagens (Type (I) and (II)), fibronectin and matrix metalloproteinases (MMPs 1, 3 and 9) [42, 43]. Here, CDH1 is linked to cancer.