ANXA8 and renal cell carcinoma: As shown in Fig. 5A, mRNA expression of ANXA8 was significantly upregulated in 786-O and 769-P, while downregulated in ACHN and CAKI-1 compared with HPTEC, indicating that 769-P and 786-O could better simulate the role of ANXA8 in RCC patients at mRNA level.