For determined the prognostic value of selected genes in HCC patients, we used the whole TCGA dataset of LIHC (374 HCC patients) for time-dependent ROC analysis, and found that the AUC scores of ACSL3, HILPDA, LPCAT1, PLIN3 and RAB10 are higher than 0.6, which revealed a well diagnostic performance of the six genes with HCC Figure S5A). This evidence concerns the gene HILPDA and hepatocellular carcinoma.