To identify a common target for B-cell lymphoma in treatment, we analyzed a CD19+ B-cell transcriptomic dataset from the Gene Expression Omnibus (GEO) database, which consists of samples from normal participants (N = 6), chronic lymphocytic leukemia (CLL, N = 5), follicular lymphoma (FL, N = 10), and diffuse large B-cell lymphoma patients (DLBCL, N = 8). The gene discussed is CD19; the disease is diffuse large B-cell lymphoma.