Different variants within the ADAMTS2 were already proven to be causative for cases of dermatospraxis EDS in humans (van Damme et al. 2016), sheep (Zhou et al. 2012; Monteagudo et al. 2015; Joller et al. 2017), cattle (Colige et al. 1999), and dogs (Jaffey et al. 2019, 2022). Here, ADAMTS2 is linked to Ehlers-Danlos syndrome.