Moreover, after having formerly shown that DNR induces NFKB2 expression in AML patients’ cells treated in vitro (Figure 1F), we established the early induction of this gene in vivo using peripheral blood mononuclear cells (PBMCs) purified from 3 AML patients before and 4 h after the beginning of an induction chemotherapy comprising DNR and Ara-C (Figure 5A). The gene discussed is NFKB2; the disease is acute myeloid leukemia.