The prognostic model for HBV+ HCC proposed in the present study was composed of 10 ferroptosis‐related genes (EPAS1 and GABARAPL1 as protective factors and SQLE, RAD51AP1, RPL8, CAPG, RRM2, SLC1A5, SLC38A1, and SRC as dangerous markers). This evidence concerns the gene SLC38A1 and hepatocellular carcinoma.