CD44 expression positivity was seen in Grades 1, 2, and 3 and most of the patients with grades 4 and 5 were negative, which corresponded to a study done by Balci et al. and Thapliyal et al [2,3]. Conversely, Thapliyal et al. did not find any statistical significance between Gleason's grading and CD44-positive expression probably due to the inclusion of an equal number of BPH (29) and prostate adenocarcinoma (30) cases in their study [2]. The gene discussed is CD44; the disease is benign prostatic hyperplasia.