We selected 18 RBPs that have been reported to bind to G4C2 repeat RNA (Mori et al., 2013a), as well as TDP-43, an ALS/FTD-linked RBP that does not bind to G4C2 repeat RNA (Xu et al., 2013; Figure 1—source data 1), and examined their roles in neurodegeneration in our C9-ALS/FTD fly models. Here, C9 is linked to frontotemporal dementia.