Similarly, Wnt-5a treatment of wounded diabetic organ-cultured corneas reduced healing time by 37% (p<0.05; Fig. 3a) vs BSA treatment (control), with acquisition of normal-like patterns of LESC markers K15 (Fig. 3b,c) and K17 (Fig. 3d), and diabetes-suppressed integrin α3β1 (Fig. 3e) and nidogen-1 (Fig. 3f). Here, NID1 is linked to diabetes mellitus.