Strikingly, transfer of RG-108-treated IL-7Rhi CD8+ T cells conferred protective immunity against YUMMER1.7 to naive mice (Fig. 5J) (P = 0.001, Log-rank test), extending the median survival from 30 d to undefined (>80 d) and led to tumor clearance in 75% of the mice (Fig. 5J). The gene discussed is CD8A; the disease is neoplasm.