Subsequent studies on cats with NPC caused by NPC1:c.2864G>C (p.C955S) showed that the oral administration of miglustat (50 mg/kg/day) was effective in reducing the accumulation of gangliosides in the brain, delaying their onset of neurological symptoms, and increasing their lifespan by approximately 74% [30]. This evidence concerns the gene NPC1 and nasopharyngeal carcinoma.