One potential candidate mRNA of this type is Wwox, which encodes a conserved WW-domain oxidoreductase that accumulates in brains of Nab2 mutant flies (Corgiat et al., 2021) and is mutated in human spinocerebellar ataxia type 12 (Serin et al., 2018; Mallaret et al., 2014). This evidence concerns the gene WWOX and spinocerebellar ataxia type 12.