PTGS2 and status epilepticus: Acute brain injuries due to status epilepticus(SE) and traumatic brain injury (TBI) create massive neuroinflammation(microgliosis, astrogliosis, and induction of cytokines, chemokines,and cyclooxygenase-2 (COX2)) in the brain,2 which will exacerbate secondary neurodegenerative pathology leadingto cognitive and behavioral deficits.