The neurodegenerative process in Alzheimer’s disease (AD) is characterized by synaptic damage leading to progressively impaired synaptic plasticity and eventual neuronal loss driven by multiple signaling abnormalities, including the overactivation of mammalian target of rapamycin (mTOR) (Guo et al., 2017). This evidence concerns the gene MTOR and early-onset autosomal dominant Alzheimer disease.