In AD versus Young samples, significantly enriched gene ontology (GO) terms included platelet alpha granule lumen (e.g., TMSB4X, PPBP, PF4, MMRN1), platelet activation (GP1BB, VCL, CD9, GP9, PF4, PLEK, GP5, MMRN1, MYL9, TREML1, UBASH3B), regulation of platelet activation (GP1BB, CD9, GP9, PLEK, GP5, MMRN1, UBASH3B) and actin cytoskeleton organization (COTL1, TMSB4X, SLC9A3R1, ARPC5, PLEK, INF2, MYL9, PARVB) (Supplementary Data S1). The gene discussed is TMSB4X; the disease is Alzheimer disease.