S100A6 and Alzheimer disease: Between AD versus Old and AD versus Young we identified 10 overlapping platelet DEPs (Figures 4A–C), including secretory vesicle proteins (ARPC5, STOM, TMSB4X, RAB14, MMRN1), proteins with cytoskeletal binding function (ARPC5, TMSB4X, RAB14, S100A6, SLC4A1) and proteins involved in platelet degranulation (TMSB4X, ENDOD1, MMRN1).