In AD versus Old samples, biological processes significantly represented included processes related to platelet function, such as actin cytoskeleton organization (ARPC3, RAC2, ACTC1, ARPC5, ROCK2, RAC1, TMSB4X, PAFAH1B1, ARPC1B) and exocytosis, but also several processes related with the immune system and neutrophil mediated immunity (Supplementary Data S1). The gene discussed is ACTC1; the disease is Alzheimer disease.