The hypothesis of NR3C1 methylation linking ELA to later life psychopathology is well established [reviewed in (106) and (97)], and an association has been observed in adults with i) borderline personality disorder (107), ii) both bulimia and borderline personality disorder (108), iii) internalizing behaviour problems, iv) arousal and excitability. This evidence concerns the gene NR3C1 and Borderline personality disorder.