Typical tumor antigens include CD19 and HLA class II in B cell malignancies, CD30 in Hodgkin lymphoma, epidermal growth factor receptor (EGFR) in various epithelial cancers, HER2 in breast cancer, and CD33 in acute myeloid leukemia (AML) (63). This evidence concerns the gene TNFRSF8 and Hodgkins lymphoma.