Omomyc has been used in its transgenic form in BL, in murine lymphoma cell lines obtained from Eμ-myc transgenic mice and in Raji cells (wild-type or knock out for FBXO11) in vitro and in vivo (subcutaneous xenografts), alone or in combination with the BCL6 degrader BI-3802[99]. This evidence concerns the gene BCL6 and lymphoma.