MECP2 and autism: In autism, examples of reported chromatin-related anomalies include mutations in genes encoding chromatin modifiers and regulators and transcription factors, such as MECP2, CHD8, ARID1B, CBX4, KDM6B, MLL3/5, SMARCC2, SETD2, MEF2A etc (O’Roak et al., 2012; Ben-David and Shifman, 2013; Parikshak et al., 2013; Bourgeron, 2015; Sahin and Sur, 2015).