Very recently, it has been shown that knocking down NaV1.6 expression significantly inhibited the proliferation, epithelial–mesenchymal transition, and invasion of follicular thyroid carcinoma (FTC), through the JAK/STAT signaling pathway (Li et al., 2022), which is associated with crucial pathological processes of tumors including cell proliferation, invasion, and apoptosis (Hu et al., 2021). The gene discussed is SCN8A; the disease is thyroid cancer, nonmedullary, 2.