Very recently, it has been shown that knocking down NaV1.6 expression significantly inhibited the proliferation, epithelial–mesenchymal transition, and invasion of follicular thyroid carcinoma (FTC), through the JAK/STAT signaling pathway (Li et al., 2022), which is associated with crucial pathological processes of tumors including cell proliferation, invasion, and apoptosis (Hu et al., 2021). Here, SCN8A is linked to thyroid gland follicular carcinoma.