Furthermore, the tumor size, TLRTP, TLRHBP, TEIHBP, T1Pre and T1HBP were also significantly different between the two groups (Table 2), of which T1HBP showed the best predictive performance for high Ki-67 LI, with an AUROC of 0.726, and sensitivity and specificity of 73.25% and 71.69% respectively (Supplementary Table S4). This evidence concerns the gene MKI67 and neoplasm.