The six identified biomarkers serum apolipoprotein A-V (ApoA5), serum miR-223, plasma heat shock protein A12B (HSPA12B), redox state of pentraxin 3 (PTX3), serum miR-133a and serum triggering receptor expressed on myeloid cells-1 (TREM-1) were initially studied in septic mice with the aim to support the subsequent clinical evaluation of their prognostic values in patients with sepsis. Here, HSPA12B is linked to Sepsis.