MCL1 and glioblastoma: To further elaborate on the apoptosis cascade, we investigated other, more clinically relevant, apoptosis inducers and observed a strong synergistic effect while combining Venetoclax (BCL targeting) and AZD5991 (MCL1 targeting).<h4>Conclusions</h4>Overall, we have identified via a high-throughput drug screening several new treatment strategies for GBM.