Among the additional and occasionally observed dementia risk predictors most noticeably missing from the leading cluster in this study were: (a) orthostatic hypotension (Anang et al., 2014; Guo et al., 2021), (b) REM sleep disorder (Dawson et al., 2018), (c) sex (Dawson et al., 2018; Phongpreecha et al., 2020), and (d) APOE (Cereda et al., 2016). The gene discussed is APOE; the disease is dementia.