Actinfilament-associatedprotein1-antisenseRNA1 (AFAP1-AS1) was significantly up-regulated in endometriosis tissues, and lncRNA-AFAP1-AS1 significantly downregulated the expression of pGL3-P886, the promoter of the transcription factor zinc-fingerE-boxbindinghomeobox1(ZTB1), promoted epithelial-mesenchymal transition (EMT), and increased ectopic endometrial invasion and implantation (128). This evidence concerns the gene AFAP1 and endometriosis.